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As for tips: Necromorphs are very slow, so if you have to deal with multiple enemies, just shoot one's legs off and focus on others. Stasis is your friend, always be mindful of stasis stations for free replenish. Your running speed is fast enough to outrun attacks from basic necromorphs, stay mobile and always reposition yourself to advantageous angles.
Force gun is a safety net. As long as you have force ammo and force gun equipped, nothing can really ambush you. Upgraded force gun kills a necromorph in 2-3 hits even on impossible. A single blast strips off flesh and muscle, rendering your enemies even slower and weaker to your other weapons. Flamethrower's (upgraded) alt fire can give you huge breathing room to deal with enemies that are attacking from multiple sides. Upgraded line gun's alt fire is also great as area of denial.
Any weapon in your inventory alters your drops so keep only 3-4 and focus on upgrading them. Be mindful of your loadout and compliment your tools. If you want to use flamethrower and force gun, the third weapon should be very good at range. Contact beam, plasma cutter, line gun.
At least two brute fights have electric floor + stasis recharge station. I don't have to say more.
What can kill your run: USM Valor has two specific rooms. The nuke warhead room, ideally you want to trigger the spawn of the exploding necromorph and then stasis it, pick up the metal rod and pin him to the wall. Remove the explosive sac with kinesis but don't throw it, just place it somewhere near the door you came from. The other exploding necro can be dealt with the second metal rod that is conveniently placed in this room.
The other Valor room is the one with constant stream of fires from the pipes in the engine room. This one is probably the worst. I would ignore the optional loot at the end of the corridor and make the U turn. Bring the kinetic cargo cube with you so that you have two for the second corridor.
You have to be careful when you go out to place the signal beacon onto the ball of rock. The two rotating pieces of machinery will kill you instantly so you have to time it right to get out. Once all 4 engines are destroyed it stops moving so you should disable the two inside first before going on a space walk.
Another instant death room is with the 3 air purifiers that have breakable door fuses. The first and last chamber are regularly ablaze but the middle one that spawns two necromorphs in is not. You can stay in the middle chamber if you get confused and lose track of the engine firing pattern.
Any electric floor is instant death. Be extra careful in any room with them and be willing to take a hit from a necromorph instead of running around like a chicken ready to be fried by damaged flooring. Same caution applies to vent blades and malfunctioning doors. Anything that can kill you instantly deserves all the time you need to deal with it. Except the centrifuge. You'll get enough air + air can to run to the end. Stasis is your friend.
The chapter 12 brute can be dealt with by bringing a few kinesis packs with you. The brute is not the problem, it's the explosive necros that come in right after it. Use stasis and some form of area of denial or force gun and you should be okay. Kill everything and then deal with the brute. You can keep the brute in stasis.
Leviathan and hive mind's attacks can be dodged by simply running/flying to either side. It requires no timing whatsoever.
I also took every single fight and never ran past any necromorphs tho lol. When you get to the last boss fight or any boss fight, all you need is the plasma cutter and a bunch of plasma cutter ammo. i'm telling you this so you dont have to worry about what arsenal of weapons you need, because the plasma cutter is gucci for all the bosses. HOW YOU PLAY IMPOSSIBLE MODE IS UP TO YOU. THERE ARE OPTIMAL ROUTES BUT YOU CAN GET THROUGH IT WHATEVER WAY YOU PLAY, JUST UNDERSTAND THIS. I WAS DEFINITELY NOT OPTIMAL AND SPAMMED THE HELL OUT OF MY AMMO NOT GONNA LIE BUT CRUISED THROUGH IMPOSSIBLE DESPITE THIS. If you want a better feeling of accomplishment, I seriously advise that you do not cheese pause and reload. It feels way better getting the achievement knowing you did it 100% legit. Good luck bruh.
I skipped from medium and went straight to impossible fyi. But I've played and completed all the other dead space games on their hardest difficulty and have completed the original dead space on impossible back in the day. dont mean to flex on ya boy. You can easily adjust from medium to impossible. But if you want to test the waters on hard difficulty first go ahead, but i wouldnt do an entire playthrough on hard just to do another playthrough on impossible. UP TO YOU THO.
I could help you out with this. (and share my work with you)
Practice makes perfect, don't jump right into impossible if you're not confident in your current skills. Play hard as long as you need until you get comfortable and more importantly, better at handling tough situations. The enemy spawns don't really change since most of it is scripted with a few dynamic spawns when backtracking. Nothing wholly new will be thrown at you.