This guide acts as challenge, Dungeon Rushers (DR) could be completed in one run, but require three things before start your journey:

• Most important, you cannot close the game or is Game Over
  
• At least have 48 hours upon your main goal is complete this game 100 % achievements
  
• Don't have electricity or light issues

Simple, the game have a problem loading your save file after the first time you close it. The Dev is trying to fix this, but sadly his domain was hacked. And he cannot do much for now.

If you see this ... well you lost your chance


Now you are warned we can start.

First of all, in DR we have 10 characters to unlock just by making progression in story. Must of them play basic roles known in D&D that will listed here a little:

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One hero could be a variant of:

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Light Melee Enemies: Easy to beat


Heavy Melee/Hybrid Enemies: Special skills are needed to weaken armor


Damage Per Turn Enemies: Usually weak but its attacks cause change party status


Heavy Magic Damage: Eliminate'em ASAP, most dangerous. Can Heal, Debuff and deal notorious damage to Party that could also inflict damage per turn.
                                                                                                                        
Always have characters specialized in their Passive talents (Tanks/Healers) and in Damage for your main front line or range characters (Sorcerers/Longe Range).
                                                                                                                        

Dungeons and Loot

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Movement is similar to a D&D board, as any dungeon map, you could find monsters and loot. In DR step in a single block one of the following encounters will be triggered: Found chest, doors, jars, traps (Avoid, resist or break), and random events that could deal positive or negative effects to our business. So be careful in made bad decissions.
                                                                         
Additionally, before enter a dungeon read carefully about the bonus challenges and aim to achieve those bonuses. I do not understand completetly what the game counts as "Succesful dungeon". But I guess that the game understands it when you collect the three jewels (blue, magenta and turqoise), one for each bonus challenge completed. However, not completing the bonus challenges do not alter your walkthrought, you can come back anytime. Do not waste your time training your characters it is not necessary.
                                                                         
Following this section will unlock these achievements: Becoming, Looter, Whipless Explorer, Master of Chest, Appetite for risk I, II, III.
                                                                                                              

My method is very simple. Download/Suscribe the below workshop map, and farm chest and events. Sadly, dev disable Exp and Gold from workshop maps. But the items and events you found still count. In this sense, complete this workshop map everytime you want, until you get a decent amount of useful stuff that could be used in your walkthrough. Dissclaimer: This part only work for early game, this map becomes useless after you making progression in story.
https://gtm.you1.cn/sharedfiles/filedetails/?id=799521307
                                                                                                              
The following step, is reach a part of story where you will unlock the crafter. Crafting in DR, is free of Gold, and some items looted in workshop map could be used here. However you will still need some times that could be found in Dungeons, but for this also I have a trick.
                                                                                                              
                                                                                                              
Go to the market and select "gamble". There are three options: low gamble (40 gold) usually give you items that are useful to crafting, medium (60 gold), sometimes throws rare weapons, armors or consumable items, high (120 gold) similar as medium but with higher % in get a rarest items. Market and its gamble option change depending in how far are in your own walkthrough. In this case, first and second options are reliable/profitable do not use third option for now. Then, sell Items you don't need, as powerful potions or beers, made expensive items by crafting them. Remember, in order to unlock "The Rich toilet cleaner" you must have 10k gold in your wallet.
                                                                                                              

                                                                                                              
Following this section will unlock these achievements: Apprentice, Craftsman, Guild Master, Place your Bets!, The Rich Toilet Cleaner, Out for Blood, Drink or Drive, you have to choose!.
                                                                                                              

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Making your own Workshop Map: Go to the map and select "My dungeons" Then create one and upload it. When you are done with this you will unlock "Budding Businessman"
                                                                                                                                                              
                                                                                                                                                              
Skills in dungeons: Use certain explore abilities/skills whilst in a dungeon Always careful, I see... I see..., Follow the Pink Rabbit.
                                                                                                                                                   

                                                                                                                                                              
A real building: Just go to the earliest/easiest tower and finish floor 5.
                                                                                                                                               

                                                                                                                                                              
Story Progression: Gnashing of Teeth, Gotta Cath'em all!, Everything has an end, Level Max!. For leveling a character to max isn't necessary to farm or train them. Just finish the campaign and play the game in heoric, it will be easier.
                                                                                                                                      

                                                                                                                                                              
The hardest one: Complete successfully all dugeons (3 jewels) and then play the whole campaing in Heoric mode (58 dungeons) "Heroic at his best".
                                                                                                                                                             

Thanks for reading this!!!
Living with depression is a little hard but it have its advantages. In 50 hours I could finish this without problem, with only 2 hours of sleep.

Is not necessary to do this, it was my condition. And you could take your time, just take it... and do not close the game.

Thanks to @Julian Lourdeaux for its art and also the Dev for clarify somethings in discussion forum. Hope you get back your domain ASAP, this game is enjoyable dispite of the save file issue. Regards.