Aguirre, the Wrath of God is a movie that ends with Klaus Kinski, noted monster both in movie and in real life, strutting around on a hopelessly lost and sinking raft, surrounded by monkeys and dead bodies. Through his own deliberate actions he is both unfathomably powerful in his own mind and a completely powerless husk of humanity by any other measure. Risk of Rain 2 is also like this but without having to look at Klaus Kinski and with co-op.