The Drunken Clam, often shortened to just The Clam, is the local Quahog bar owned by Jerome and formerly Horace. It is the favorite hangout of Peter Griffin, Glenn Quagmire, Cleveland Brown, Joe Swanson and sometimes Peter's dog Brian Griffin. There is also the new addition of fourth friend, Jerome, who met the guys there. They drink copious quantities of Pawtucket Patriot beer, watch TV and chew the fat, away from the women.

In "Meet the Quagmires", Death shows up when Horace falls off his ladder in the Clam, whilst trying to fix the TV - Horace is only knocked unconscious. This allows Peter to ask Death to return him to the 1980s, so he can live a wild youth. Part of that experience includes visiting the 1980s bar - then called St Elmo's Clam a reference to the electrical phenomenon, and to the song, "St Elmo's Fire". Here Peter plays "Menstrual Ms. Pacman", meets and makes out with Molly Ringwald, and joins Cleveland at an evening disco. This contradicts its appearance in "One if by Clam, Two if by Sea", where in that 1984, it was still The Drunken Clam.