The centered ubercharge meter and patient health are better for situational awareness, the default centered is pretty good but I think its too far down on the screen, the larger monitors get the harder it is to see anything closer to the edges.

Change these values in hudlayout.res Just modify the y position to move it up and down
" HudMedicCharge //change ypos to raise charge
"xpos" "c-90"
"ypos" "c10" //def 88


CMainTargetID // medic target crosshair health viewer
"xpos" "c-126"
"ypos" "228" //def 300 under 275 over 228


CSecondaryTargetID //medic target patient health
"xpos" "c-126"
"ypos" "280" //def 360 under 300 over 280"

add this to your autoexec so you can refresh the hud in game to check your changes instantly hitting the - key.
bind - "hud_reloadscheme"


https://gtm.you1.cn/sharedfiles/filedetails/?id=1441033116
This is how it looks healing a patient with the vaccination where seeing the resist icon at a glance is important

https://gtm.you1.cn/sharedfiles/filedetails/?id=1441032510
This is how it looks like while viewing other team members health

A version just scrunched up below, I prefer above.
https://gtm.you1.cn/sharedfiles/filedetails/?id=1441040607