I'm sure they would if Seamus or any other creature/past creature was willing. I really don't think they have any collabs set in stone just yet considering the fact that they just started their channel.

They well prolly play with the Creatures through the Let's Play channel.

That's gonna be awkward even if they don't want it to be. Although they departed on good terms, members of/ the creatures took a hit in subs and total views which CowChop was the reason for.